跳到主要內容區

副系主任的話

 

 

張玉喆 副系主任

張玉喆

隨著醫學知識不斷更新,病人照顧模式也必須與時俱進,社會對醫師專業能力的期許就更高了,這是一個挑戰,也是各位和所有醫學系師長共同的目標,如何幫助大家具備醫學專業素養,從學校教育到臨床場域的病人照護,能展現出符合期待的能力進展,這是需要大家共同努力的。面對跨領域的照護模式,需要學習好溝通能力及領導力,未來幾年將是各位建構專業認同的關鍵時期,參與臨床實作可以了解醫師工作的價值與信仰,以及在專業領域及社會上所扮演的角色,這也是支持各位實現夢想的力量。不論學習、生活、人際關係及臨床工作上,如果遭遇到挑戰,我鼓勵大家一定要正向思考,勇於面對,系上有很多師長都是各個專業領域的典範,能夠引導大家走在正確的方向,系上也還有很多資源能夠協助大家克服困難,成功自己定義,美好的未來就在不遠處。

 現職/學歷/經歷

現職
長庚大學     醫學系     副系主任
林口長庚醫院 急診醫學部 主治醫師
長庚醫學教育研究中心    副主任

學歷
國立陽明大學 醫學系 學士
國立陽明大學 急重症醫學研究所碩士
澳洲福林德斯大學
(Flinders University) 臨床教育碩士

經歷
2017~迄今 長庚大學醫學系專任副教授
2015~迄今 林口長庚醫院急診醫學部住院醫師訓練計畫主持人
2014~2019 林口長庚醫院臨床技能中心主任
2012~2017 長庚大學醫學系專任助理教授
2011~迄今 林口長庚醫院專責教學主治醫師
2005~迄今 林口長庚醫院急診醫學部主治醫師
2002~2005 台北榮總急診醫學部住院醫師
1999~2002 台北榮總兒童醫學部住院醫師

學會經歷
2020~迄今 台灣醫學教育學會副秘書長 
2020~迄今 急診專業發展工作小組副召集人 
2010~迄今 急診醫學會檢傷工作小組委員 
2016~2022 急診醫學會兒童急症委員會主任委員 
2012~2016 急診醫學會急診學習里程碑委員會員
2006~2010 急診醫學會教育委員會委員 

專長與研究領域

專長
急診醫學、兒童急診醫學、醫學教育、高擬真情境模擬教學

研究領域
兒童檢傷分類、急診管理、迷你臨床演練、專業認同與復原力、擬真教學、選科決策、性別議題

期刊論文(近5年)

  1. Liu TT, Cheng CT, Hsu CP, Chaou CH, Ng CJ, Jeng MJ, Chang YC*. Validation of a five-level triage system in pediatric trauma and the effectiveness of triage nurse modification: A multi-center cohort analysis. Front Med (Lausanne). 2022 Nov 1;9:947501. doi: 10.3389/fmed.2022.947501. eCollection 2022.
  2. Hu CY, Nisbet G, Chang YC*. Responding to change in a medical student rural community service: Insights from activity theory. Med Educ. 2022 Nov;56(11):1086-1095. doi: 10.1111/medu.14869. 
  3. Lo HY, Lin SC, Chaou CH, Chang YC, Ng CJ, Chen SY. What is the impact of the COVID-19 pandemic on emergency medicine residency training: an observational study. BMC Med Educ. 2022 Oct 18;22(1):727. doi: 10.1186/s12909-022-03786-w.
  4. Chang YL, Hsieh MJ, Chang YC, Yeh SL, Chen SW, Tsai YF. Self-efficacy of caring for patients in the intensive care unit with delirium: Development and validation of a scale for intensive care unit nurses. Aust Crit Care. 2022 Sep 19:S1036-7314(22)00117-5. doi: 10.1016/j.aucc.2022.08.006. Online ahead of print.
  5. Chao YP, Kang CJ, Chuang HH, Hsieh MJ, Chang YC, Kuo TBJ, Yang CCH, Huang CG, Fang TJ, Li HY, Lee LA. Comparison of the effect of 360° versus two-dimensional virtual reality video on history taking and physical examination skills learning among undergraduate medical students: a randomized controlled trial. Virtual Real. 2022 Aug 16:1-14. doi: 10.1007/s10055-022-00664-0. Online ahead of print.
  6. Kumar K, Roberts C, Finn GM, Chang YC. Using theory in health professions education research: a guide for early career researchers. BMC Med Educ. 2022 Aug 4;22(1):601. doi: 10.1186/s12909-022-03660-9.
  7. Chang YC, Nkambule NS, Chen SY, Hsieh MJ, Chaou CH. Exploring the Impact of Pre-course High-Fidelity Simulation on Professional Socialization of Medical Students in Emergency Medicine Internship Rotation-A Qualitative Approach. Front Med (Lausanne). 2022 Jun 30;9:933212. doi: 10.3389/fmed.2022.933212. eCollection 2022.
  8. Chang YC, Chuang RS, Hsiao CT, Khwepeya M, Nkambule NS. Bridging the Gap: Using Consensus to Explore Entrustment Decisions and Feedback Receptivity in Competency-Based Emergency Medicine Residency Programs Through the Construction of a Q-Sample Incorporating a Delphi Technique. Front Med (Lausanne). 2022 Jun 2;9:879271. doi: 10.3389/fmed.2022.879271. eCollection 2022.
  9. Liu P, Chen SY, Chang YC, Ng CJ, Chaou CH. Multimodal In-training Examination in an Emergency Medicine Residency Training Program: A Longitudinal Observational Study. Front Med (Lausanne). 2022 Mar 9;9:840721. doi: 10.3389/fmed.2022.840721. eCollection 2022.
  10. Huang YB, Lin YR, Hung SK, Chang YC, Ng CJ, Chen SY. Pediatric Training Crisis of Emergency Medicine Residency during the COVID-19 Pandemic. Children (Basel). 2022 Jan 1;9(1):32. doi: 10.3390/children9010032.
  11. Yau SY, Chang YC, Wu MY, Liao SC. Does seniority always correlate with simulated intubation performance? Comparing endotracheal intubation performance across medical students, residents, and physicians using a high-fidelity simulator. PLoS One. 2021 Sep 24;16(9):e0257969. doi: 10.1371/journal.pone.0257969. eCollection 2021.
  12. Chang YC, Nkambule NS, Xiao X, Ngerng RYL, Monrouxe LV. Safety net, gateway, market, sport, and war: Exploring how emergency physicians conceptualize and ascribe meaning to emergency care. Soc Sci Med. 2021 Oct;287:114338. doi:10.1016/j.socscimed.2021.114338. Epub 2021 Aug 27. 
  13. Chen SY, Chaou CH, Yu SR, Chang YC, Ng CJ, Liu P. High-fidelity simulation is associated with good discriminability in emergency medicine residents' in-training examinations. Medicine (Baltimore). 2021 Jun 18;100(24):e26328. doi: 10.1097/MD.0000000000026328 
  14. Chaou CH, Yu SR, Chang YC, Ma SD, Tseng HM, Hsieh MJ, Fang JT. The evolution of medical students' preparedness for clinical practice during the transition of graduation: a longitudinal study from the undergraduate to postgraduate periods. BMC Med Educ. 2021 May 6;21(1):260. doi: 10.1186/s12909-021-02679-8. 
  15. Hsu PW, Fu RH, Chang YC. Comparing learning outcomes among postgraduate year trainee groups. Biomed J. 2020 Dec;43(6):490-495. doi: 10.1016/j.bj.2019.10.002. Epub 2020 Oct 22. 
  16. Lo HY, Lin SC, Chaou CH, Chang YC, Ng CJ, Chen SY. What is the impact of the COVID-19 pandemic on emergency medicine residency training: an observational study. BMC Med Educ. 2020 Oct 7;20(1):348. doi: 10.1186/s12909-020-02267-2. 
  17. Lo HY, Chaou CH, Chang YC, Ng CJ, Chen SY. Prediction of emergency department volume and severity during a novel virus pandemic: Experience from the COVID-19 pandemic. Am J Emerg Med. 2020 Aug 5:S0735-6757(20)30679-3. doi: 10.1016/j.ajem.2020.07.084. 
  18. Chaou CH, Yu SR, Ngerng RYL, Monrouxe LV, Chang LC, Chang YC*. Clinical Teachers’ Motivations For Feedback Provision in Busy Emergency Departments: A Multi-center Qualitative Study. Emerg Med J 2020 July accepted. 
  19. Chen WC, Chaou CH, Ng CJ, Liu YP, Chang YC*. Assessing the effectiveness of pediatric emergency medicine education in emergency medicine residency training: A national survey. Hong Kong J Emerg Med. 2020 June 4. Online ahead of print.
  20. Chang YC, Xiao X, Nkambule N, Ngerng RYL, Bullock A, Monrouxe LV. Exploring emergency physicians' professional identities: a Q-method study. Adv Health Sci Educ Theory Pract. 2020 May 7. doi: 10.1007/s10459-020-09973-y. Online ahead of print.
  21. Chang YC, Tseng HM, Xiao X, Ngerng RYL, Wu CL, Chaou CH. Examining the association of career stage and medical specialty with personality preferences - a cross-sectional survey of junior doctors and attending physicians from various specialties. BMC Med Educ. 2019 Sep 23;19(1):363.
  22. Chang YC, Chou LT, Lin HL, Huang SF, Shih MC, Wu MC, Wu CL, Chen PT, Chaou CH. An interprofessional training program for intrahospital transport of critically ill patients: model build-up and assessment. J Interprof Care. 2019 Jan 23:1-5
  23. Chen HJ, Liao LL, Chang YC, Hung CC, Chang LC. Factors Influencing Technology Integration in the Curriculum for Taiwanese Health Profession Educators: A Mixed-Methods Study. Int J Environ Res Public Health. 2019 Jul 22;16(14)
  24. Chaou CH, Chang YC, Yu SR, Tseng HM, Hsiao CT, Wu KH, Monrouxe LV, Ling RNY. Clinical learning in the context of uncertainty: a multi-center survey of emergency department residents' and attending physicians' perceptions of clinical feedback. BMC Med Educ. 2019 May 29;19(1):174
  25. Anderson MB, Crampton P, Hejri SM, Chang YC. Introduction May 2019 - 'Really Good Stuff'. Med Educ. 2019 May;53(5):496-497
  26. Chen KS, Monrouxe L, Lu YH, Jenq CC, Chang YJ, Chang YC, Chai PY. Academic outcomes of flipped classroom learning: a meta-analysis. Med Educ. 2018 Jun 25
  27. Chang, Y. C., Lee, C. H., Chen, C. K., Liao, C. H., Ng, C. J., Chen, J. C., & Chaou, C. H. (2017). Exploring the influence of gender, seniority and specialty on paper and computer-based feedback provision during mini-CEX assessments in a busy emergency department. Adv Health Sci Educ Theory Pract. 2017 Mar;22(1):57-67
  28. Chaou CH, Monrouxe LV, Chang LC, Yu SR, Ng CJ, Lee CH, Chang YC*. Challenges of feedback provision in the workplace: A qualitative study of emergency medicine residents and teachers. Med Teach. 2017;39:1145-1153.

研究計畫

計畫主持人

  1. 駕馭臨床不確定:從容忍和有效處理臨床不確定的視角來探究醫師的執業準備度及幸福感

     科技部研究計畫編號:110-2511-H-182 -004 -MY3
     執行期間:
2021.08.01-2024.07.31

  1. 運用高擬真情境模擬教學為實習醫師做好應對臨床不確定之準備

     教學實踐研究計畫編號:PMN1100582
     執行期間:
2021.08.01-2022.07.31

  1. 運用高擬真情境模擬教學作為醫學生急診醫學臨床實習低參與度之可能補救方法 –一個自我決定論的研究

     教學實踐研究計畫編號:PMN1090331
     執行期間:
2020.08.01-2021.07.31

  1. 發展高擬真情境模擬作為醫學生照顧急重症病人之信賴評核工具

     教學實踐研究計畫編號:PMN1080027
     執行期間:
2019.08.01-2020.07.31

  1. 實施基於以能力為導向的醫學教育評估作為潛在的專業認同強化之工具:探究可信賴的專業活動/學習里程碑評估的可行性及其對急診醫師專業認同的影響

     科技部研究計畫:MOST 108-2511-H-182 -007 -MY2   
     執行期間:
2019.08.01-2021.07.31

  1. 建構有復原力的工作人力:探索急診醫師的專業認同,職業倦怠和壓力的關係

     科技部研究計畫:105-2511-S-182-001-MY3   
     執行期間:
2016.08.01-2019.12.31

  1. 急重症團隊擬真教育對各級學員~急處置能力的學習成效與學習機轉分析- 一個混合方法研究

     長庚醫學研究計畫:CDRPG1G0014   
     執行期間:
2017.08.01-2019.07.31

  1. 運用高擬真情境模擬訓練提升醫學生急診學習成效-探究學習反應與專業認同

     教育部教學實踐研究計畫:PMN107014   
     執行期間:
2018.08.01-2019.07.31

  1. 建構急重症病患院內轉送跨領域訓練模式及實地評量成效初探

     長庚醫學研究計畫:CMRPG3E0121   
     執行期間:
2015.10.01-2016.09.30

  1. 探討畢業後第一年住院醫師專科選擇之動態歷程及決策支援策略之成效評估

     長庚醫學研究計畫:CMRPG3E0061   
     執行期間:
2015.08.01-2016.07.30

計劃共同主持人

  1. 模擬情境教學對加護病房護理人員的譫妄自我效能及批判性思考能力之成效-隨機臨床試驗

     科技部研究計畫:109-2314-B-182 -009 -MY3
     執行期間:
2020/08/01~2023/07/31

  1. 可信賴專業活動導向的評量工具開發,驗證和可行性測試於勝任能力導向的急診醫學訓練

     科技部研究計畫:107-2511-H-182 -003 -MY2
     執行期間:
2018/08/01~2020/07/31

  1. 急診病患年齡層別檢傷分類系統研究-分類錯置、處置修正、模型驗證

     科技部研究計畫:104-2410-H-182-028-MY2
     執行期間:
2013.08.01-2015.07.31

  1. 急診低中緊急檢傷級數病患之後續住院相關因素與預測模型研究

     科技部研究計畫:102-2410-H-182-010-MY2
     執行期間:
2015.08.01-2017.07.31

  1. 台灣地區急診住院醫師臨床教學口頭回饋現狀調查與影響因子探討之多中心研究

     科技部研究計畫
     執行期間:
2016.08.01-2017.07.31

專書章節著作

  1. 史青平、朱宗藍、吳茂昌、李石增、李明勳、周蘭娣、林秋子、林益豪、徐鵬偉等(201108月)。評量後回饋。臨床能力評量指引(ISBN:9789866052040)。台灣愛思唯爾。
  2. 李石增、李靜宜、林孟志、徐鵬偉、陳德全、陳國書、許俊傑、張玉喆、張寓智、傅仁煇、歐良修、鄭昌錡、賴宏逸、謝明儒、蕭政廷(2011年)。模擬醫學。長庚臨床教師TOTR工作坊(補充教材)。長庚醫療財團法人。
  3. 王大民、王智亮、江明洲、余光輝、余男文、李丞騏、李振宏、沃宏達、林宗男等(2011年)。第17章 外傷急症;第18章 技術操作。OSCE實例。

曾獲得之學術獎勵

  1. 林口長庚醫院100年度最優教師。
  2. 林口長庚醫院102年度優良教學主治醫師。
  3. 長庚大學103年度教學奬優良教師。
 

 

林蔚然 副系主任

林蔚然

得天下英才而教之是人生一大樂事,很高興能成為醫學系師長的一員。我的工作是協助校長,院長,系主任及大學同仁推動醫學系的運作及革新。希望長庚醫學系學生的求學時光,除了學習到豐富的知識外,也能擁有快樂的大學生活,找到自己人生的方向。

 現職/學歷/經歷

現職
長庚大學     醫學系       部定教授暨副系主任
林口長庚醫院 胃腸肝膽科系 學術組教授暨胃腸科主任
林口長庚醫院 肝臟研究中心 副中心主任

學歷
中國醫藥大學 醫學系 學士
英國倫敦大學 瑪莉皇后學院 分子生物醫學博士

經歷
2022~迄今 林口長庚醫院胃腸科主任
2022~迄今 林口長庚醫院肝臟研究中心副主任
2021~迄今 長庚大學醫學系部定教授
2020~迄今 林口長庚醫院胃腸肝膽科系教授
2020~迄今 長庚大學醫學系副系主任
2020~迄今 林口長庚醫院內科部整合醫學發展小組負責人
2018~2020 內科醫學會學習里程碑委員
2017~2021 長庚大學醫學系部定副教授
2015~2020 林口長庚醫院胃腸肝膽科系副教授
2013~2017 長庚大學醫學系部定助理教授
2013~迄今 林口長庚醫院內科部PGY副負責人
2011~2015 林口長庚醫院胃腸肝膽科系助理教授
2008~2011 林口長庚醫院胃腸肝膽科系講師
2005~迄今 林口長庚醫院胃腸肝膽科系主治醫師
2000~2005 林口長庚醫院內科部住院醫師及胃腸肝膽科系總醫師

專長與研究領域

專長
胃腸肝膽疾病之診療,胃鏡大腸鏡及息肉切除,減重內視鏡操作。
醫學教育,整合醫學。

研究領域
幹細胞,粒線體,能量代謝,微菌叢,癌症及消化道疾病相關基礎研究。消化道疾病大數據臨床研究。

期刊論文(近5年)

  1. Yeh CS, Hsu CW, Liang KH, Chen YC, Lin CL, Chien RN, Hu TH, Lin WR, Lai MW, Chu YD, Yeh CT*. Development of a fibrosis index including hepatitis B virus basal core promoter A1762T mutation for pretherapeutic evaluation. J Gastroenterol Hepatol. 2018 Aug;33(8):1530-1537
  2. Alison MR*, Lin WR. (Co-first) Macrophages come on tap for liver fibrosis therapy. Hepatology. 2018 Sep;68(3):1194-1196.
  3. Lai MW, Hsu CW, Lin CL, Chien RN, Lin WR, Chang CS, Liang KH, Yeh CT*. Multiple doses of hepatitis B recombinant vaccine for chronic hepatitis B patients with low surface antigen levels: a pilot study. Hepatol Int. 2018 Sep;12(5):456-464.
  4. Chen TH, Lin WR*, Lee C, Chiu CT, Hsu JT, Yeh TS, Lin KH, Le PH, Yeh CT*. Prognostic Stratification of Advanced Gastric Signet Ring Cell Carcinoma by Clinicopathological Factors and GALNT14 Genotype. J Cancer. 2018 Sep 8;9(19):3540-3547.
  5. Alison MR*, Lin WR. Bile ductular reactions in the liver: similarities are only skin deep. J Pathol. 2019 Jul;248(3):257-259.
  6. Li HT, Lee CH, Wu T, Cheng MY, Tseng WJ, Chang CW, Hsieh HY, Chiang HI, Lin CY, Chang BL, Lin WR, Lim SN*. Clinical, Electroencephalographic Features and Prognostic Factors of Cefepime-Induced Neurotoxicity: A Retrospective Study. Neurocrit Care. 2019 Oct;31(2):329-337.
  7. Alison MR*, Lin WR. Periportal SRY (Sex Determining Region Y)-Box 9-Positive Hepatocytes: Progenitors With a Biliary Leaning. Hepatology. 2019 Oct;70(4):1470-1473
  8. Lin WR*, Chiang JM, Lim SN, Su MY, Chen TH, Huang SW, Chen CW, Wu RC, Tsai CL, Lin YH, Alison MR, Hsieh SY, Yu JS, Chiu CT, Yeh CT. Dynamic bioenergetic alterations in colorectal adenomatous polyps and adenocarcinomas. EBioMedicine. 2019 Jun;44:334-345.
  9. Chen CW, Chiu CT, Su MY, Lin CJ, Hsu CM, Lim SN, Yeh CT, Lin WR*. Factors associated with polyp detection during colonoscopy: A retrospective observational study. Kaohsiung J Med Sci. 2019 Sep;35(9):572-577.
  10. Lee KC, Lin CL, Hsu CW, Chang ML, Chen YC, Lin WR, Lai MW, Lin KH, Chao M, Chien RN, Yeh CT*. Decreasing seroprevalence of anti-hepatitis D virus antibodies in the antiviral era with inverse association with hepatitis B virus DNA, Taiwan, 2006 to 2019. J Med Virol. 2019 Aug 30. doi: 10.1002/jmv.25582.
  11. Chiang CC, Yeh CT, Hwang TL, Chu YD, Lim SN, Chen CW, Kuo CJ, Le PH, Chen TH, Lin WR*. The GALNT14 genotype predicts postoperative outcome of pancreatic ductal adenocarcinoma. J Clin Med 2019, 8, 2225; doi:10.3390/jcm8122225 
  12. Li HT, Wu T, Lin WR, Lim SN*. Response to "Cefepime-Induced Encephalopathy: A Possible Additional Mechanism of Neurotoxicity". Neurocrit Care. 2020 Apr;32(2):642.
  13. Lin WR, Yeh CT*. GALNT14: An Emerging Marker Capable of Predicting Therapeutic Outcomes in Multiple Cancers. Int J Mol Sci. 2020 Feb 21;21(4):1491. (SCI; IF=4.556; Biochemistry&Molecular Biology 74/297)
  14. Huang HC, Lin WR*, Lim SN, Yeh CT, Yen TH, Alison MR, Chen CS*. (Co-corresponding) Aldolase Triggers Metabolic Reprogramming in Colorectal Cancer in Hypoxia and Stiff Desmoplastic Microenvironments. Colloids Surf B Biointerfaces. 2020 Jun;190:110969.
  15. Chu YD, Lin WR (co-first), Lin YH, Kuo WH, Tseng CJ, Lim SN, Huang YL, Huang SC, Wu TJ, Lin KH, Yeh CT*. COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma. Cancers (Basel). 2020 Jun 22;12(6):1646.
  16. Liang KH, Cheng ML, Lo CJ, Lin YH, Lai MW, Lin WR, Yeh CT*. Plasma phenylalanine and glutamine concentrations correlate with subsequent hepatocellular carcinoma occurrence in liver cirrhosis patients: an exploratory study. Sci Rep. 2020 Jul 2;10(1):10926.
  17. Kuo CJ, Lin CY, Le PH, Chang PY, Lai CH, Lin WR, Chang ML, Hsu JT, Cheng HT, Tseng CN, Lin CJ, Su MY, Hsieh SY, Chiu CT*. Rescue therapy with rifabutin regimen for refractory Helicobacter pylori infection with dual drug-resistant strains. BMC Gastroenterol. 2020 Jul 10;20(1):218.
  18. Chen CW, Kuo CJ, Chiu CT, Su MY, Lin CJ, Le PH, Lim SN, Yeh CT, Alison MR, Lin WR*. The effect of prophylactic hemoclip placement and risk factors of delayed post-polypectomy bleeding in polyps sized 6 to 20 millimeters: a propensity score matching analysis. BMC Gastroenterol. 2020 Sep 22;20(1):309.
  19. Lin YH, Chu YD, Lim SN, Chen CW, Yeh CT, Lin WR*. Impact of an MT-RNR1 Gene Polymorphism on Hepatocellular Carcinoma Progression and Clinical Characteristics. Int J Mol Sci. 2021 Jan 23;22(3):1119.
  20. Lim SN, Wu T, Tseng WJ, Chiang HI, Cheng MY, Lin WR, Lin CN. Efficacy and safety of perampanel in refractory and super-refractory status epilepticus: cohort study of 81 patients and literature review. J Neurol. 2021 Oct;268(10):3744-3757.
  21. Shao C, Shao PP, Chen WT, Lin CC, Lin WR*, Yeh CT*. Direct-acting Antiviral Therapy Improves the Outcome of Chronic Hepatitis C/intermediate-stage B Hepatocellular Carcinoma Patients. Anticancer Res. 2021 Apr;41(4):2007-2016.
  22. Kuo CJ, Lee CH, Chang ML, Lin CY, Lin WR, Su MY, Chiu CH, Tseng CN, Wu YS, Chiu CT, Lai CH. Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection. J Microbiol Immunol Infect. 2021 Dec;54(6):1184-1187.
  23. Liang KH, Lai MW, Lin YH, Chu YD, Lin CL, Lin WR, Huang YH, Wang TH, Chien RN, Hu TH, Yeh CT. Plasma interleukin-17 and alpha-fetoprotein combination effectively predicts imminent hepatocellular carcinoma occurrence in liver cirrhotic patients. BMC Gastroenterol. 2021 Apr 17;21(1):177.
  24. Turan AS, Pohl H, Matsumoto M, Lee BS, Aizawa M, Desideri F, Albéniz E, Raju GS, Luba D, Barret M, Gurudu SR, Ramirez FC, Lin WR, Atsma F, Siersema PD, van Geenen EJM; Prophylactic Clipping Collaborative Group. The Role of Clips in Preventing Delayed Bleeding After Colorectal Polyp Resection: An Individual Patient Data Meta-Analysis. Clin Gastroenterol Hepatol. 2022 Feb;20(2):362-371.
  25. Yu LS, Jhunjhunwala M, Hong SY, Yu LY, Lin WR*, Chen CS*. Tissue Architecture Influences the Biological Effectiveness of Boron Neutron Capture Therapy in In Vitro/In Silico Three-Dimensional Self-Assembly Cell Models of Pancreatic Cancers. Cancers (Basel). 2021 Aug 12;13(16):4058.
  26. Kuo CJ, Lin CY, Chen CW, Hsu CY, Hsieh SY, Chiu CT, Lin WR*. Risk of Enteric Infection in Patients with Gastric Acid Supressive Drugs: A Population-Based Case-Control Study. J Pers Med. 2021 Oct 22;11(11):1063.
  27. Chu YD, Kee KM, Lin WR, Lai MW, Lu SN, Chung WH, Pang ST, Yeh CT. SYNE1 Exonic Variant rs9479297 Contributes to Concurrent Hepatocellular and Transitional Cell Carcinoma Double Primary Cancer. Biomedicines. 2021 Dec 2;9(12):1819.
  28. Chu YD, Lim SN, Yeh CT, Lin WR*. COX5B-Mediated Bioenergetic Alterations Modulate Cell Growth and Anticancer Drug Susceptibility by Orchestrating Claudin-2 Expression in Colorectal Cancers. Biomedicines. 2021 Dec 28;10(1):60.
  29. Lin YH, Lim SN, Chen CY, Chi HC, Yeh CT, Lin WR*. Functional Role of Mitochondrial DNA in Cancer Progression. Int J Mol Sci. 2022 Jan 31;23(3):1659.
  30. Yeh PJ, Wu RC, Chiu CT, Lai MW, Chen CM, Pan YB, Su MY, Kuo CJ, Lin WR, Le PH. Cytomegalovirus Diseases of the Gastrointestinal Tract. Viruses. 2022 Feb 8;14(2):352.
  31. Ho PH, Hsiao HC, Chen CW, Chen HM, Lim SN, Yeh CT, Kuo CJ, Lin WR*. Anticoagulant drugs with or without proton pump inhibitor and colorectal cancer risk: a population-based, case-control study. BMC Gastroenterol. 2022 May 9;22(1):225.

研究計畫

計畫主持人

  1. CMRP: CMRPG370721&0722                   03/01/2008-02/28/2010

          The role of bone marrow stem cell in pancreatic fibrosis and therapeutic effect.

  1. NMRP: NMRPG3A0201                      08/01/2011-07/31/2012

          Tracing stem cell lineages in human gastrointestinal epithelial tumors and tissues.

  1. CMRP: CMRPG3A0921~ 0923                 01/10/2011-30/09/2014

          The role of mitochondrial function and mitochondrial DNA mutation in liver cancer stem cells and hepatocellular carcinoma.

  1. CMRP: CMRPG3B0471                       02/01/2012-31/03/2013

          To evaluate the anti-fibrotic effect of G-CSF through BM stem cell mobilisation and engraftment in a mouse model of pancreatic fibrosis

  1. NMRP: NMRPD1B1601~ 1602                  08/01/2012-07/31/2014

          The role of mitochondrial function and DNA mutation in chronic hepatitis B

  1. CMRP: CMRPG3B0801~ 0803                  10/01/2012-03/31/2016

          The role of mitochondrial function and mitochondrial DNA mutation in colon polyps and colorectal cancer stem cell

  1. 跨世紀醫療促進基金會: SMRPG3C0011     04/15/2013-10/31/2014

          To evaluate the anti-fibrotic effect of induced pluripotent stem cells in a mouse model of pancreatic fibrosis

  1. NMRP: NMRPD1D0491                         08/01/2014-07/31/2015

          The role of mitochondrial function and DNA mutation in colorectal carcinogenesis

  1. CMRP: CMRPG3E1461                          06/01/2015~05/31/2016

          To evaluate the anti-fibrotic effect of desacyl ghrelin in a mouse model of pancreat fibrosis

  1. CMRP: CMRPG3E2181                           12/01/2015~04/30/2017

          The role of mitochondria function and DNA mutation in colorectal carcinogenesis (2nd and 3rd                    years)

  1. CMRP: CMRPG3F1401 ~1403                     06/01/2016~07/31/2019

          To use tumor-specific mitochondrial DNA mutations in hepatocellular carcinoma as a personalized serum biomarker for identifying tumor recurrence

  1. CMRP: CMRPG3F0061 ~0063                     08/01/2016~07/31/2019

          The defects of cytochrome c oxidase may contribute to liver cancer recurrence and metastasis through increasing Ras/MAPK pathway

  1. CORP: CORPG3F0241                          12/01/2016~11/30/2017

          The comparison of colonscopic quality between patients with deep sedation and patients with clear consciousness

  1. CORP: CORPG3G0501                             10/01/2017~05/31/2019

          The correlation between post-polypectomy bleeding and prophylactic hemoclip application

  1. CMRP: CMRPG3H0241                   01/01/2018~12/31/2018

          The interconnection of metabolisms, extracellular matrix and mechanotransduction in colorectal cancer

  1. NMRP: NRRPG3H0011                    08/01/2018-10/31/2019

          The association between prognosis and bioenergetic alterations of colon mucosa, polyps and colorectal cancers

  1. CORP: CORPG3H0161                     10/01/2018~06/30/2020

          The Association between Clinical presentation of Small Intestinal Tumor and Prognosis

  1. CORP: CORPG3I0011                       01/01/2019~12/31/2019

          The correlations between microenvironment rigidity and bioenergetic alteration on colorectal cancer

  1. CMRP: CMRPG3J0691                    08/01/2019~07/31/2020

          The role of aldolase, fructose-bisphosphate B and solute carrier family 16 member 4 in colorectal cancer

  1. CORP: CORPG3J0501                     10/01/2019~09/30/2020

          The use of clopidogrel, low-dose aspirin and proton pump inhibitor in reducing the risk of colorectal cancer.

  1. NMRP: NRRPG3K0061                    08/01/2020~07/31/2021

          To study the mechanisms of how the behaviors of hepatocellular carcinoma are controlled by the core subunit of oxidative phosphorylation, and the feasibility of using proteins of the downstream pathway as cancer target therapy.

  1. NMRP: NRRPG3L0091          08/01/2021~07/31/2022

          To investigate the roles of bioenergetic alteration in colorectal cancer: using the key protein of mitochondrial oxidative phosphorylation, cytochrome c oxidase subunit 5B, as a research model

  1. CORP: CORPG3L0271          10/01/2021~01/31/2023

          The risk factors of GI malignancies in patients with bariatric therapies

  1. NMRP: NRRPG3M0141         08/01/2022~07/31/2023

          To investigate the roles of ALDOB-mediated bioenergetic alterations in colorectal cancer: Mechanisms behind Warburg effect

曾獲得之學術獎勵

2012 跨世紀醫療促進基金會 醫學研究獎 
201422屆歐洲聯合消化系醫學周 傑出論文壁報獎
2014 林口長庚醫院 優良教師
2017 美國消化系學會 榮譽院士 (Fellow of AGA) 
2018 林口長庚醫院 優良服務人員 
2020 林口長庚醫院 資深優良教師  
2020 台灣消化系醫學會年會 優秀論文壁報獎第一名 
2019,2020,2021,2022 林口長庚醫院 優秀論文獎 
2022 台灣消化系醫學週 研究論文 會長獎